Nothing, really! How to Make Nachos in the Oven. Top with the remaining cheese and then the chips. Top with half of the cheese and half of the chips. Bake for about 10 to 12 minutes, or until the cheese has melted. Stir in salsa, corn, mayonnaise and chili powder. Preheat oven to 350F. Click HERE to save this recipe for Ultimate Easy Nachos to Pinterest!. Instructions. What is easier than covering a baking tray with crunchy tortilla chips, topping it with spicy refried beans and cheese, and popping it in the oven for a few minutes? In a large skillet, cook ground beef over medium high heat until cooked. Spread half of the beef mixture in the prepared casserole. Spoon the remaining meat mixture evenly over the chip later.